The REACTION BIOLOGY CORP BRD4 Full Length protein is a human recombinant bromodomain-containing protein 4 that plays a significant role in transcriptional regulation and cell cycle progression. This protein, produced in Sf9 insect cells, features N-terminal His and C-terminal StrepII tags, enabling specific binding to ε-N-acetyllysine residues. Mainly recognized for its function in chromatin regulation, cancer research, and inflammation studies, BRD4 is also an atypical kinase that phosphorylates RNA Polymerase II.
- Produced in Sf9 insect cells
- Active transcriptional regulator
- Contains two bromodomains
- Has a molecular weight of 156.5 kDa
- Tagged with N-terminal His and C-terminal StrepII
- Purity exceeds 85% by SDS-PAGE
- Stored at -70°C or -80°C
- Functionally important for BET bromodomain studies